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Abstract

In this work we focused on the synthesis of new Azo-Schiff bases which were prepared by condensation of 3-formyl-4-hydroxy phenylazo benzene with both 1,4-Bis (3- aminopropyl) piprazine, thiocarbohydazide respectively. The Schiff bases were analyzed by different spectral techniques (LC-MS, GC-MS, 1H-NMR, IR). The new Azo-Schiff Bases were studied for antibacterial activities against gram positive (Bacillus subtilis and Staphylococcus aureus) and gram negative (Salmonella typhi and Escherichia coli) agents. The azo compound ligand exhibited a variable activity of inhibition on the growth of the bacteria. The compounds were subjected to simultaneous thermogravimetric analysis to study their decomposition mechanism and thermal stability.

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