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Abstract

A series containing sixteen titled pyrazoline derivatives have been synthesized by perchloric acid catalyzed cyclization cum acetylation of 3-hydroxyphenyl chalcones, hydrazine hydrate and acetic anhydride by refluxing condition. The yields of the synthesized N-acetylpyrazolines were found to be more than 90%. These 1-acetylpyrazolines were characterized by their physical constants and spectral data. The antioxidant activities of these pyrazolines derivatives have been evaluated by 2,2- diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity.

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